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Half-Life and drug interactions: Implications for polypharmacy and adverse reactions

Ruiz Hensler

Drug interactions occur when two or more drugs are taken together, and their effects on the body are altered. This can lead to adverse reactions or even treatment failure. One of the factors that determine the occurrence and severity of drug interactions is the half-life of the drugs involved. Half-life refers to the time it takes for the concentration of a drug in the body to decrease by half.