抽象的

Unveiling the mysteries of salmonella typhi: the bacterium behind typhoid fever

Hannah Nicole*

Salmonella species generate significant morbidity, mortality, and disease burden worldwide. Salmonella infections induce a variety of clinical symptoms. The activation of a significant host innate immune/inflammatory response is central to the pathogenesis of all human salmonellosis. It is unclear whether this eventually reflects an adaptive advantage for the host or pathogen. It is clear, however, that both the host and the pathogen have evolved mechanisms for inducing host reactions that are harmful to the other. Some of the host and pathogenic mechanisms that are involved in the two most common clinical syndromes associated with Salmonella enteric infection: enterocolitis and typhoid. Salmonella nomenclature is complicated, and scientists refer to and communicate about this genus using many ways. However, consistency in Salmonella nomenclature is required for communication among scientists, health officials, and the general public. Unfortunately, current usage frequently blends different nomenclatural systems that divide the genus inconsistently into species, subspecies, subgenera, groupings, subgroups, and serotypes (serovars), causing confusion. The CDC receives several enquiries about the proper Salmonella nomenclature for reporting results and use in scholarly papers.