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Genetic association of IL-8 (rs4073) gene polymorphism with susceptibility to chronic periodontitis: A case control study in south Indian population

Vidyashri S, Sankari Malaiappan*, Vijayashree Priyadharshini, Karthikeyan Murthy kumar

Many environmental and bacterial factors are in the initiation and modulation of periodontal disease. Recent studies show increasing evidence that genes also play a vital role in the etiology and progression of periodontal diseases. Interleukin 8 is a neutrophil chemotactic agent that mediates the inflammatory reaction in periodontal disorders. The present study was done to analyse the association of IL8 polymorphism with periodontitis patients.