抽象的

Blood path-physiological changes of women suffering from female genital schistosomiasis in parts of coastal regions of Kenya

Jimmy Kihara

Female Genital Schistosomiasis (FGS) apparent in vulval, vaginal and/or cervical areas has been reported from endemic areas. Studies have shown common manifestation in S. haematobium infection, with prevalence rate ranging from 30% to 75% (Steinmann, 2006). Pregnant or lactating women infected may be complicated further by malnutrition, anaemia and low immunity (Olds, 2003) resulting in more pathophysiological changes. This was a cross sectional study where a total of 394 Women of reproductive age (16 – 45 years) were recruited in the study. Urine was examined using nucleopore filtration method to diagnose S. haematobium. Blood was analysed using automated haematology analyzer. Malaria slides were examined to rule out infection. Pregnant women had higher prevalence and intensity of infection with urinary schistosomiasis than non-pregnant women. Presence of anaemia was 65.2% in pregnant women and 22.2% in non-pregnant women (Z=8.46, P<0.001) while RBC count, 52.3% in pregnant women and 14.1% in non-pregnant women (Z=6.39, P<0.001). Levels of Eosinophilia were slightly higher in infected pregnant women than infected non-pregnant women, the same was observed for thrombocytosis. In conclusion, female genital schistosomiasis causes anemia among pregnant women, as well as blood patho-physiological and this could be associated with the subtle disease progression. Biography: Jimmy Kihara is a medical parasitologist, with many years of experience in parasite, epidemiology, diagnosis and control in various countries including and not limited to India, Pakistan, Gambia, Ghana, Uganda etc. In the past 15 years I have been involved in control of STH and Schistosomiasis in School age children in Kenya, Pakistan and India. Currently I am an associate senior research scientist with Kenya Medical Research Institute. Together with other scientists we have published many papers in peer review journals. Currently I am interested in parasite control and more so Female Genital Schistosomiasis which affects this vulnerable group in the society. Recent Publications: 1. Effectiveness of albendazole on soil transmitted nematodes among school children-: a case of Kakamega County, Kenya, African Journal of Health Sciences, Vol. 32 No. 1 (2019) 2. Use of Rapid Diagnostic Tests in Malaria School Surveys in Kenya: Does their Under-performance Matter for Planning Malaria Control?, The American Journal of Tropical Medicine and Hygiene, Volume 87, Issue 6, 5 Dec 2012, p. 1004 – 1011. 3. actors Associated with the Performance and Cost-Effectiveness of Using Lymphatic Filariasis Transmission Assessment Surveys for Monitoring Soil-Transmitted Helminths: A Case Study in Kenya, The American Journal of Tropical Medicine and Hygiene, Volume 92, Issue 2, 4 Feb 2015, p. 342 – 353 4. Urogenital schistosomiasis in women of reproductive age and pregnant mothers in Kwale County, Kenya, Published online by Cambridge University Press: 08 October 2013